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Mebicar 1000mg

Mebicar

CAS 10095-06-4  ·  C₈H₁₄N₄O₂  ·  MW 198.22 g/mol

Ładowanie molekuły...

O związku Mebicar 1000mg

Mebicar 1000mg (Mebicar) to związek chemiczny zarejestrowany pod numerem CAS 10095-06-4 o wzorze sumarycznym C₈H₁₄N₄O₂ i masie molowej 198.22 g/mol.

Cząsteczka zawiera 28 atomów połączonych 29 wiązaniami chemicznymi. Pełna nazwa systematyczna IUPAC dla tego związku to 1,3,4,6-tetramethyl-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione. Powyższy interaktywny model 3D pozwala obejrzeć układ przestrzenny atomów — można go obracać przeciągnięciem myszką, powiększać scrollem oraz przełączać między trybami wizualizacji szkieletowy / Ball & Stick / Space Fill.

Pod względem właściwości fizykochemicznych współczynnik podziału logP = -0.9 (wartość ujemna, związek hydrofilowy), powierzchnia polarna PSA = 47.1 Ų, 0 donorów i 2 akceptorów wiązań wodorowych. Te parametry są kluczowe przy ocenie biologicznej dostępności i interakcji z biomolekułami.

Dane chemiczne dla tego związku pochodzą z PubChem (NIH NLM NCBI), jednej z największych baz związków chemicznych na świecie. Wszystkie informacje są aktualizowane automatycznie i wzbogacone o polskie tłumaczenia zwrotów GHS zgodne z Rozporządzeniem CLP (1272/2008/WE). Powyższy widget można używać do celów edukacyjnych, badawczych i komercyjnych.

Właściwości fizykochemiczne

Wzór sumaryczny	C8H14N4O2
Masa molowa	198.22 g/mol
IUPAC	1,3,4,6-tetramethyl-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione
SMILES	—
InChIKey	XIUUSFJTJXFNGH-UHFFFAOYSA-N
logP (XLogP3)	-0.9
PSA	47.1 Ų
HBD / HBA	0 / 2
PubChem CID	CID 122282 ↗

Bezpieczeństwo GHS

Sygnał:

GHS07

Drażniący / Szkodliwy

H302 — Działa szkodliwie po połknięciu

Literatura naukowa

Literatura naukowa

15 artykułów · 1 open access · Źródła: PubMed, OpenAlex, Semantic Scholar

🔓

[An experience of using mebicar in patients with autonomic dysfunction associated with anxiety disorder].

Zhitkova JV, Hasanova DR (2017) · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova

Open AccessDOI ↗PubMed ↗PDF ↗

Preventive Effect of Mebicar and Ginsenoside Rg1 on Neurobehavioral and Immunological Disruptions Caused by Intermittent Unpredictable Stress in Mice.

Kim CY, Kim YG, Sin SJ et al. (2018) · Neuroimmunomodulation

$ PaywallDOI ↗PubMed ↗

[Anti-inflammatory effects of amitriptyline, diazepam and mebicar using model of acute carrageenan-induced paw edema in rats].

Kaziakhmetova VN, Valeeva IKh, Ziganshina LE (2011) · Eksperimental'naia i klinicheskaia farmakologiia

$ PaywallPubMed ↗

[Experimental comparative study of the analgesic activity of the diurnal anxiolytic mebicar, amitriptyline, and diazepam].

Khaziakhmetova VN, Luchai KV, Ziganshina LE (2015) · Eksperimental'naia i klinicheskaia farmakologiia

$ PaywallPubMed ↗

[Characteristics of the psychotropic spectrum of action of mebicar].

Val'dman AV, Zaikonnikova IV, Kozlovskaia MM et al. (1980) · Biulleten' eksperimental'noi biologii i meditsiny

$ PaywallPubMed ↗

[Quantitative ceriometric determination of mebicar].

Pavlova VM, Berliand AS, Knizhnik AZ (1979) · Farmatsiia

$ PaywallPubMed ↗

[Adaptol--verges of possible].

Mkrtchian VR, Kozhokova LZ (2012) · Likars'ka sprava

Review$ PaywallPubMed ↗

[Effect of the tranquilizer mebicar on lipid metabolism and lipid peroxidation in a rat hypokinesic model].

Zamakova IE, Salikhova RR, Tagirova TS et al. (1996) · Biulleten' eksperimental'noi biologii i meditsiny

$ PaywallPubMed ↗

[Evaluation of the tranquilizing effect of phenazepam and mebicar in humans using a method of mean cortical evoked potential after perception of emotionally significant words].

Val'dman AV, Kostandov EA, Martynikhin AV (1983) · Biulleten' eksperimental'noi biologii i meditsiny

$ PaywallPubMed ↗

[Effect of mebikar on focal epileptic activity].

Rekhtman MB, Torshin VI, Darinskiĭ NV (1981) · Biulleten' eksperimental'noi biologii i meditsiny

$ PaywallPubMed ↗

TREATMENT OPTIMIZATION IN MANAGEMENT OF COMBINED PATHOLOGY - ARTERIAL HYPERTENSION AND POST-COVID SYNDROME IN ELDERLY PATIENTS.

Kazakov YM, Potiazhenko MM, Nastroga TV (2023) · Wiadomosci lekarskie (Warsaw, Poland : 1960)

$ PaywallDOI ↗PubMed ↗

[An analysis of the cardiovascular reactions due to mebikar].

Kamburg RA (1990) · Farmakologiia i toksikologiia

$ PaywallPubMed ↗

Effectiveness of psychopharmacotherapy in psoriasis patients with associated anxiety and depression.

Matiushenko VP, Kutasevych YF, Havryliuk OA et al. (2020) · Dermatologic therapy

$ PaywallDOI ↗PubMed ↗

[Protective effect of the psychotropic preparations diazepam, sodium oxybutyrate and mebikar in experimental arrhythmias].

Kamburg RA, Zimakova IE (1982) · Farmakologiia i toksikologiia

$ PaywallPubMed ↗

[Experimental and clinical study of the effectiveness of the combined use of anticonvulsants and tranquilizers in epilepsy].

Zalesov VS, Prostakova TI, Khvolis EA et al. (1988) · Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952)

$ PaywallPubMed ↗

Dane z PubMed (NIH NLM), OpenAlex (CC0), Semantic Scholar (AI2). AI Summary wygenerowane przez Semantic Scholar TLDR. Artykuły z ikoną wymagają płatnego dostępu.

Synonimy

Mebicar · 10095-06-4 · mebikar · Tetramethylglycoluril · Tetrahydro-1,3,4,6-tetramethylimidazo(4,5-d)imidazole-2,5(1H,3H)-dione · 55FE6NPG89 · Glycoluril, 1,3,4,6-tetramethyl- · imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetramethyl- · 2,4,6,8-tetramethyl-2,4,6,8-tetraazabicyclo-(3.3.0)-octan-3,7-dione · Imidazo(4,5-d)imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetramethyl- · RefChem:810813 · DTXCID1066079 · (3as,6as)-1,3,4,6-tetramethyl-octahydro-(1,3)diazolo(4,5-d)imidazole-2,5-dione · Temgicoluril · 1,3,4,6-Tetramethyltetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione

Źródła danych

• 📊 PubChem CID 122282 — NIH
• 🔬 NIST WebBook — spektroskopia
• 🌐 Wikidata
• 💊 ChEMBL — bioaktywność

Kup w sklepie

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